Question 21M.2.HL.TZ1.f
| Date | May 2021 | Marks available | [Maximum mark: 1] | Reference code | 21M.2.HL.TZ1.f |
| Level | HL | Paper | 2 | Time zone | TZ1 |
| Command term | Suggest | Question number | f | Adapted from | N/A |
Some anticancer drugs inhibit mitosis by blocking the formation of the spindle. Suggest one other way in which vinblastine could block mitosis.
[1]
a. causes microtubules/spindle fibres to break up / tubulin molecules to depolymerize ✔
b. prevents contraction of spindle microtubules/fibres ✔
c. disrupts/damages kinetochores/centromeres/microtubule motors/centrioles/centrosomes ✔
d. prevents separation/pulling apart of (sister) chromatids/chromosomes/centromeres ✔
e. prevents microtubules/spindle binding to chromatids/chromosomes/centromeres/DNA ✔
Mark the first suggestion only in the answer.
Do not allow answers about DNA replication or other processes that precede mitosis.
A wide range of possible ways in which mitosis could be blocked was accepted and about a third of candidates suggested one of these. Methods of blocking DNA replication or cytokinesis were not accepted as the question specifically referred to mitosis.
