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Question 18N.2.HL.TZ0.d.ii

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Date November 2018 Marks available [Maximum mark: 1] Reference code 18N.2.HL.TZ0.d.ii
Level HL Paper 2 Time zone TZ0
Command term Suggest Question number d.ii Adapted from N/A
d.ii.
[Maximum mark: 1]
18N.2.HL.TZ0.d.ii

Mutagens can be removed from the body by converting them to readily excreted metabolites. NNK is converted to a metabolite, NNAL-Gluc, which can be used as a biomarker for the uptake of NNK. Cotinine, a metabolite of nicotine, is an indicator of tobacco smoke uptake. The graph shows the relationship between these two metabolites in the urine of 233 smokers.

Suggest one advantage of using the urine concentration of cotinine rather than NNAL-Gluc to give a measure of the amount of tobacco smoke inhaled by a person.

[1]

Markscheme

higher «concentrations» so easier to measure/identify/find
OR
wider spread/greater range «of values/concentrations»
OR
units are larger/nmol rather than pmol ✔

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