Question 23M.2.HL.TZ2.18
| Date | May 2023 | Marks available | [Maximum mark: 2] | Reference code | 23M.2.HL.TZ2.18 |
| Level | HL | Paper | 2 | Time zone | TZ2 |
| Command term | Outline | Question number | 18 | Adapted from | N/A |
Outline how these drug administration methods affect bioavailability.
Oral: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Intravenous: . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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[2]
Oral:
low/lower «bioavailability» AND drugs pass through digestive system «and breakdown» ✓
Intravenous:
high/higher «bioavailability» AND «more» direct route to bloodstream ✓
Accept “low/lower AND drugs not easily absorbed from digestive system”
OR
“low/lower AND drugs broken down in digestive system”
OR
“low/lower AND drugs affected by acid” for M1.
Do not penalize use of “slow” for “low/lower” or “fast” for “high/higher”.
Accept “100 % bioavailability” for “high/higher” within Intravenous answer in M2.
Award [1 max] for “oral drugs have slower absorption/distribution than intravenous drugs”
OR
“Oral: low/lower «bioavailability» AND intraveneous: high/higher «bioavailability»”.