Question 17N.3.HL.TZ0.10
| Date | November 2017 | Marks available | [Maximum mark: 6] | Reference code | 17N.3.HL.TZ0.10 |
| Level | HL | Paper | 3 | Time zone | TZ0 |
| Command term | Identify, Outline, State, Suggest | Question number | 10 | Adapted from | N/A |
The table shows a comparison of DNA base sequences in several yeast (Saccharomyces) genomes.
[Source: P. F. Cliften et al. (2001) ‘Surveying Saccharomyces Genomes to Identify Functional Elements by Comparative DNA Sequence Analysis’, Genome Research, 11, pp. 1175–1186. © Cold Spring Harbor Laboratory Press. Reproduced with permission.]
Identify the species that has the lowest percentage of coding sequences.
[1]
S. unisporus
State how similar nucleotide sequences can be identified.
[1]
BLASTn/sequence alignment software
“n” required in BLASTn
The yeast Saccharomyces cerevisiae was the first eukaryotic organism to have its entire genome sequenced. Suggest reasons for the choice of yeast as a study organism.
[3]
a. easy to grow
OR
easy/cheap to produce large amounts
OR
fast generation time
b. genomes are small/easy to manipulate
c. metabolically diverse
d. industrial applications/biopharming
e. no ethical issues «with yeast»
[Max 3 Marks]
Outline possible medical applications of the polymerase chain reaction (PCR).
[1]
a. identify different viral/influenza strains
b. genetic testing/testing for genetic disease mutations
c. tissue typing
d. vaccine development
[Max 1 Mark]