DP Biology (last assessment 2024)
Question 19N.3.HL.TZ0.b
| Date | November 2019 | Marks available | [Maximum mark: 3] | Reference code | 19N.3.HL.TZ0.b |
| Level | HL | Paper | 3 | Time zone | TZ0 |
| Command term | Explain | Question number | b | Adapted from | N/A |
b.
[Maximum mark: 3]
19N.3.HL.TZ0.b
Explain the use of a viral vector in gene therapy.
[3]
Markscheme
a. gene therapy involves introducing a normal copy of a defective gene into an organism ✔
b. virus/viral vector «genetically» modified for «safe» use ✔
c. insertion of desired gene/allele into viral genome/retrovirus ✔
d. an example is the use in SCID/lack of enzyme ADA in SCID ✔
e. removal of somatic cells ✔
f. introduction and insertion of the desired gene into the target cell
OR
modified virus can be introduced in the form of «inhaled» droplets
OR
the cells are introduced in the patient so that the desired gene can be expressed ✔
