DP Biology (last assessment 2024)
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6.5 Neurons and synapses

Description

Nature of science:
Cooperation and collaboration between groups of scientists—biologists are contributing to research into memory and learning. (4.3)Understandings:

  • Neurons transmit electrical impulses.
  • The myelination of nerve fibres allows for saltatory conduction.
  • Neurons pump sodium and potassium ions across their membranes to generate a resting potential.
  • An action potential consists of depolarization and repolarization of the neuron.
  • Nerve impulses are action potentials propagated along the axons of neurons.
  • Propagation of nerve impulses is the result of local currents that cause each successive part of the axon to reach the threshold potential.
  • Synapses are junctions between neurons and between neurons and receptor or effector cells.
  • When presynaptic neurons are depolarized they release a neurotransmitter into the synapse.
  • A nerve impulse is only initiated if the threshold potential is reached.

Applications and skills:

  • Application: Secretion and reabsorption of acetylcholine by neurons at synapses.
  • Application: Blocking of synaptic transmission at cholinergic synapses in insects by binding of neonicotinoid pesticides to acetylcholine receptors.
  • Skill: Analysis of oscilloscope traces showing resting potentials and action potentials.

Guidance:

  • The details of structure of different types of neuron are not needed.
  • Only chemical synapses are required, not electrical, and they can simply be referred to as synapses.

Utilization:

  • An understanding of the workings of neurotransmitters and synapses has led to the development of numerous pharmaceuticals for the treatment of mental disorders.

Syllabus and cross-curricular links:
Biology
Topic 1.4 Membrane transport
Chemistry
Topic C6 Electrochemistry, rechargeable batteries and fuel cells
Psychology
Core: Biological level of analysis

Aims:

  • Aim 8: The social effects of the abuse of psychoactive drugs could be considered, as could the use of the neurotoxin Botox for cosmetic treatments.

 


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