DP Chemistry (last assessment 2024)
Question 19N.3.hl.TZ0.26b
Date | November 2019 | Marks available | [Maximum mark: 1] | Reference code | 19N.3.hl.TZ0.26b |
Level | hl | Paper | 3 | Time zone | TZ0 |
Command term | Describe | Question number | b | Adapted from | N/A |
b.
[Maximum mark: 1]
19N.3.hl.TZ0.26b
Taxol is an anticancer drug.
(b)
Describe how the challenge in (a) was resolved by pharmaceutical companies.
[1]
Markscheme
chiral auxiliaries/molecule binds to reactant blocking one reaction site «by steric hindrance»
OR
asymmetric synthesis / enantioselective catalysis «producing a specific enantiomer»
OR
biosynthesis / genetically modified bacteria/microorganisms ✔
NOTE: Accept “use of a chiral auxiliary leading to «the synthesis of» the desired enantiomer”.
