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Question 17N.3.sl.TZ0.18

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Date November 2017 Marks available [Maximum mark: 2] Reference code 17N.3.sl.TZ0.18
Level sl Paper 3 Time zone TZ0
Command term Outline Question number 18 Adapted from N/A
18.
[Maximum mark: 2]
17N.3.sl.TZ0.18

New drugs undergo thorough clinical trials before they are approved.

(a)

Outline the difference between the therapeutic index in animal studies and the therapeutic index in humans.

[1]

Markscheme

in animal studies LD50 ED50  AND in humans  TD50 ED50

OR

in animal studies lethal dose/LD50 AND in humans toxic dose/TD50

(b)

State the method of drug administration that gives the maximum bioavailability.

[1]

Markscheme

intravenous/IV «injection»

OR

injection into the bloodstream