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Question 17N.3.hl.TZ0.11b.i

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Date November 2017 Marks available [Maximum mark: 2] Reference code 17N.3.hl.TZ0.11b.i
Level hl Paper 3 Time zone TZ0
Command term Suggest Question number b.i Adapted from N/A
b.i.
[Maximum mark: 2]
17N.3.hl.TZ0.11b.i

An enzyme catalyses the conversion of succinate to fumarate ions in a cell, as part of the process of respiration.

The rate of the reaction was monitored and the following graph was plotted.

(b.i)

The malonate ion acts as an inhibitor for the enzyme.

Suggest, on the molecular level, how the malonate ion is able to inhibit the enzyme.

[2]

Markscheme

similar shape/size/structure «as succinate ion/substrate»

competes for the active site «with the succinate ion/substrate»

Accept “competitive inhibitor” for M2.

Award [1 max] if non-competitive inhibition is correctly described.