DP Chemistry (last assessment 2024)

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Question 17N.3.hl.TZ0.23b

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Date November 2017 Marks available [Maximum mark: 3] Reference code 17N.3.hl.TZ0.23b
Level hl Paper 3 Time zone TZ0
Command term Explain Question number b Adapted from N/A
b.
[Maximum mark: 3]
17N.3.hl.TZ0.23b

Some drugs are extracted from natural sources and others are synthetic.

(b)

Explain the role of the chiral auxiliary in the synthesis of Taxol.

[3]

Markscheme

Any three of:

chiral auxiliary is optically active

is attached to non-optically active/non-chiral substrate

creates stereochemical condition necessary to follow a certain pathway

allows only the required enantiomer to form «so avoids need to separate a racemic mixture»

[Max 3 Marks]

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