DP Chemistry (last assessment 2024)
Question 19M.3.hl.TZ1.a(i)
| Date | May 2019 | Marks available | [Maximum mark: 1] | Reference code | 19M.3.hl.TZ1.a(i) |
| Level | hl | Paper | 3 | Time zone | TZ1 |
| Command term | Draw | Question number | a(i) | Adapted from | N/A |
a(i).
[Maximum mark: 1]
19M.3.hl.TZ1.a(i)
This question is about antiviral drugs.
Oseltamivir, used for the treatment of severe flu, is inactive until converted in the liver to its active carboxylate form.
Draw a circle around the functional group that can be converted to the carboxylate by hydrolysis.
[1]
Markscheme
[✔]
Note: Accept circles that include the alkyl side chain.
Examiners report
Required candidates to identify the functional group in a diagram of the structure of oseltamivir that can be converted to a carboxylate by hydrolysis. This was very challenging with many varied parts of the structure circled. Many circled the amide group. Candidates who selected the ester had to be careful to not include the ring structure as well.
