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Question 19M.3.hl.TZ1.a(ii)

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Date May 2019 Marks available [Maximum mark: 1] Reference code 19M.3.hl.TZ1.a(ii)
Level hl Paper 3 Time zone TZ1
Command term Deduce Question number a(ii) Adapted from N/A
a(ii).
[Maximum mark: 1]
19M.3.hl.TZ1.a(ii)

This question is about antiviral drugs.

Oseltamivir, used for the treatment of severe flu, is inactive until converted in the liver to its active carboxylate form.

The resulting active metabolite of oseltamivir can be detected by mass spectrometry (MS) analysis.

Deduce the mass of the expected carboxylate ion.

Mr oseltamivir = 312

[1]

Markscheme

283  [✔]

Examiners report

The challenge continued where the expected mass of the carboxylate ion was required. Some candidates chose values that exceeded the molar mass of oseltamivir itself, and some chose 45. There were very few correct answers.