DP Chemistry (last assessment 2024)

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Question 19N.3.hl.TZ0.b

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Date November 2019 Marks available [Maximum mark: 1] Reference code 19N.3.hl.TZ0.b
Level hl Paper 3 Time zone TZ0
Command term Describe Question number b Adapted from N/A
b.
[Maximum mark: 1]
19N.3.hl.TZ0.b

Taxol is an anticancer drug.

Describe how the challenge in (a) was resolved by pharmaceutical companies.

[1]

Markscheme

chiral auxiliaries/molecule binds to reactant blocking one reaction site «by steric hindrance»
OR
asymmetric synthesis / enantioselective catalysis «producing a specific enantiomer»
OR
biosynthesis / genetically modified bacteria/microorganisms ✔

NOTE: Accept “use of a chiral auxiliary leading to «the synthesis of» the desired enantiomer”.