DP Chemistry (last assessment 2024)

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Question 17N.3.sl.TZ0.11

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Date November 2017 Marks available [Maximum mark: 4] Reference code 17N.3.sl.TZ0.11
Level sl Paper 3 Time zone TZ0
Command term Explain Question number 11 Adapted from N/A
11.
[Maximum mark: 4]
17N.3.sl.TZ0.11

Enzyme activity depends on many factors. Explain how pH change causes loss of activity of an enzyme.

[4]

Markscheme

conformation/shape altered

OR

active site altered

OR

tertiary structure altered

acidic/basic/ionizable/COOH/carboxyl/NH2/amino groups in the R groups/side chains «react»

exchange/lose/gain protons/H+

ionic/H-bonds altered

Accept “substrate doesn't fit/fits poorly into active site” OR “enzyme denatures” for M1 but not “affects potential of
enzyme to form complex with substrate”.