Question 17N.3.SL.TZ0.17
| Date | November 2017 | Marks available | [Maximum mark: 5] | Reference code | 17N.3.SL.TZ0.17 |
| Level | SL | Paper | 3 | Time zone | TZ0 |
| Command term | Outline, State | Question number | 17 | Adapted from | N/A |
The graph shows the relationship between gastrointestinal (GI) damage and gastric acidity in 37 healthy human volunteers.
[Source: Republished with permission of Elsevier Science and Technology Journals, from ‘Integrated gastric acidity can predict the prevention of naproxen-induced gastroduodenal pathology in normal subjects’, John Plachetka, Gaetano Morelli, Carolyn Hines, Julie Borland, Alison Lyke, Diane Littlefield, Jerry D. Gardner Gastroenterology, Vol. 124, Issue 4, 2003; permission conveyed through Copyright Clearance Center, Inc.]
State the relationship between gastric acidity and GI damage.
[1]
probability of GI damage increases with increased «gastric» acidity
OR
positive correlation
OWTTE
Do not accept “directly proportional”
GI damage can include ulcers. Outline the treatment of stomach ulcers.
[3]
a. proton pump inhibitors reduce stomach acid «production»
b. antacid/medication to neutralize/decrease acidity
c. «lower acidity» allow GI damage/ulcers to heal
d. antibiotics for H. pylori/bacterial infection
e. diet/lifestyle changes/eliminate smoking/alcohol
f. surgery needed with extensive gastric damage
Accept “cauterization” for marking point f
[Max 3 Marks]
Other than gastric acidity, state a primary cause of stomach ulcers.
[1]
a. Helicobacter pylori/H. pylori «infection»
b. use of non-steroidal anti-inflammatory drugs/NSAID/aspirin/ibuprofen
Accept valid examples of NSAID but do not accept trade names
[Max 1 Mark]