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Question 17N.3.HL.TZ0.a.ii

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Date November 2017 Marks available [Maximum mark: 4] Reference code 17N.3.HL.TZ0.a.ii
Level HL Paper 3 Time zone TZ0
Command term Explain Question number a.ii Adapted from N/A
a.ii.
[Maximum mark: 4]
17N.3.HL.TZ0.a.ii

Explain how the normal production of bile pigments changes with the development of jaundice.

[4]

Markscheme

normal production: [2 max]

a. red blood cells/erythrocytes/hemoglobin broken down «in the liver»

b. hemoglobin/heme «from red blood cells» is converted to bilirubin/bile pigment

c. bilirubin/bile pigment transferred to bile and «normally» eliminated in the feces

change with jaundice:

d. «in jaundice» liver does not excrete/eliminate bilirubin/bile pigments

e. caused by immaturity/dysfunction/disease «of the liver»

    OR

    blockage of bile ducts

    OR

    increase in red blood cells breakdown

f. therefore bilirubin/bile pigment accumulates in the blood

[Max 4 Marks]