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Question 18M.3.HL.TZ2.a

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Date May 2018 Marks available [Maximum mark: 2] Reference code 18M.3.HL.TZ2.a
Level HL Paper 3 Time zone TZ2
Command term Discuss Question number a Adapted from N/A
a.
[Maximum mark: 2]
18M.3.HL.TZ2.a

A long term study followed nearly 40 000 apparently healthy young men for coronary heart disease (CHD) from adolescence through adulthood. The results show how the body mass index (BMI) at adolescence and adulthood affect the risk of CHD. The BMIs are divided into five groups (quintiles), Q1 being the lowest BMI and Q5 the highest. A risk factor of 2 or less is desirable.

Using the graph, discuss the hypothesis that a high BMI in adolescence is more dangerous than a high BMI in adulthood.

[2]

Markscheme

Hypothesis supported as:

a. all subjects with a high BMI «in Q5» in adolescence had a high risk of CHD «>6», even when BMI in adulthood was low «in Q2» 
OWTTE.

b. subjects with a high BMI in adulthood «Q4 and Q5» had a much higher risk of CHD if they also had a high BMI in adolescence 
OWTTE.

c. high BMI in both adolescence and adulthood increases risk

Accept any other valid answer based on the graph.

[Source: From The New England Journal of Medicine, A Tirosh et al, Adolescent BMI Trajectory and Risk of
Diabetes versus Coronary Disease, 364, 1315. Copyright © (2011) Massachusetts Medical Society.
Reprinted with permission from Massachusetts Medical Society]