20.2 Synthetic routes

Explain why the major organic product is 2-bromopropane and not 1-bromopropane.

Explain why the major organic product is 2-bromopropane and not 1-bromopropane.

Explain why the major organic product is 2-bromopropane and not 1-bromopropane.

The minor product, C₆H₅–CH₂–CH₂Br, can be directly converted to an intermediate compound, X, which can then be directly converted to the acid C₆H₅–CH₂–COOH.

C₆H₅–CH₂–CH₂Br → X → C₆H₅–CH₂–COOH

Identify X.

The minor product, C₆H₅–CH₂–CH₂Br, can be directly converted to an intermediate compound, X, which can then be directly converted to the acid C₆H₅–CH₂–COOH.

C₆H₅–CH₂–CH₂Br → X → C₆H₅–CH₂–COOH

Identify X.

The minor product, C₆H₅–CH₂–CH₂Br, can be directly converted to an intermediate compound, X, which can then be directly converted to the acid C₆H₅–CH₂–COOH.

C₆H₅–CH₂–CH₂Br → X → C₆H₅–CH₂–COOH

Identify X.

Which statement best describes retrosynthesis?

A.  The reaction conditions needed to convert the product of a reaction back to the starting materials.

B.  Synthesizing a target molecule by working back from the target molecule to the starting materials.

C.  A synthetic scheme using traditional methods rather than modern methods and materials.

D.  A synthetic pathway which favours the equilibrium towards the products.

Which statement best describes retrosynthesis?

A.  The reaction conditions needed to convert the product of a reaction back to the starting materials.

B.  Synthesizing a target molecule by working back from the target molecule to the starting materials.

C.  A synthetic scheme using traditional methods rather than modern methods and materials.

D.  A synthetic pathway which favours the equilibrium towards the products.

Propene is reacted first with hydrogen chloride to produce X which is then reacted with aqueous sodium hydroxide to give Y. Finally, Y is reacted with excess acidified potassium dichromate solution.

$$\text{C}{\text{H}}_{\text{3}}\text{CHC}{\text{H}}_{\text{2}}\stackrel{\text{HCL}}{\to }\text{X}\stackrel{\text{NaOH(aq)}}{\to }\text{Y}\stackrel{{\text{H}}^{+}/\text{C}{\text{r}}_2{{\text{O}}_7}^{2-}\text{(aq)}}{\to }\text{Z}$$

What is the major product, Z? 

A.     CH₃CH(OH)CH₃

B.     CH₃COCH₃

C.     CH₃CH₂CHO

D.     CH₃(CH₂)₂COOH

Propene is reacted first with hydrogen chloride to produce X which is then reacted with aqueous sodium hydroxide to give Y. Finally, Y is reacted with excess acidified potassium dichromate solution.

$$\text{C}{\text{H}}_{\text{3}}\text{CHC}{\text{H}}_{\text{2}}\stackrel{\text{HCL}}{\to }\text{X}\stackrel{\text{NaOH(aq)}}{\to }\text{Y}\stackrel{{\text{H}}^{+}/\text{C}{\text{r}}_2{{\text{O}}_7}^{2-}\text{(aq)}}{\to }\text{Z}$$

What is the major product, Z? 

A.     CH₃CH(OH)CH₃

B.     CH₃COCH₃

C.     CH₃CH₂CHO

D.     CH₃(CH₂)₂COOH

Propanone can be synthesized in two steps from propene. Suggest the synthetic route including all the necessary reactants and steps.

Propanone can be synthesized in two steps from propene. Suggest the synthetic route including all the necessary reactants and steps.

Propanone can be synthesized in two steps from propene. Suggest the synthetic route including all the necessary reactants and steps.

Propanone can be synthesized in two steps from propene.

Suggest why propanal is a minor product obtained from the synthetic route in (g)(i).

Propanone can be synthesized in two steps from propene.

Suggest why propanal is a minor product obtained from the synthetic route in (g)(i).

Propanone can be synthesized in two steps from propene.

Suggest why propanal is a minor product obtained from the synthetic route in (g)(i).

Sketch the mechanism for the reaction of propene with hydrogen bromide using curly arrows.

Sketch the mechanism for the reaction of propene with hydrogen bromide using curly arrows.

Sketch the mechanism for the reaction of propene with hydrogen bromide using curly arrows.

Explain why the major organic product is 2-bromopropane and not 1-bromopropane.

Explain why the major organic product is 2-bromopropane and not 1-bromopropane.

Explain why the major organic product is 2-bromopropane and not 1-bromopropane.