DP Biology (first assessment 2025)

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Question 19M.2.HL.TZ2.2b.i

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Date May 2019 Marks available [Maximum mark: 2] Reference code 19M.2.HL.TZ2.2b.i
Level HL Paper 2 Time zone TZ2
Command term Outline Question number b.i Adapted from N/A
b.i.
[Maximum mark: 2]
19M.2.HL.TZ2.2b.i
(b.i)

Outline the difference in methylation pattern between tumorous and normal tissue samples.

 

[2]

Markscheme

a. «overall» much more methylation in the colon tumour samples than normal ✔

b. tumour and normal samples the markers 258 and 269 similar degree of methylation/fewer differences ✔

c. degree of methylation on certain markers may correlate with the presence of cancer / correct example of a marker only methylated in tumour cells eg marker 32 ✔

Examiners report

Many students detected that greater degrees of methylation in tumour samples. Fewer could accurately summarize the specific differences between methylation in the two samples.

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