DP Biology (first assessment 2025)
Question SPM.2.HL.TZ0.8
Date | May Specimen-2023 | Marks available | [Maximum mark: 15] | Reference code | SPM.2.HL.TZ0.8 |
Level | HL | Paper | 2 | Time zone | TZ0 |
Command term | Describe, Explain, Outline | Question number | 8 | Adapted from | N/A |
8.
[Maximum mark: 15]
SPM.2.HL.TZ0.8
There are a number of advantages to specificity.
(a)
Explain how vaccination can result in specific immunity to a viral disease.
[7]
Markscheme
- vaccinations are specific to a specific disease;
- vaccines contain non-self antigens/antigens from pathogens;
- can be live relative/attenuated version of the virus;
- trigger a primary immune response (without causing the disease);
- lymphocytes with specific receptors (are activated and) produce memory cells;
- (memory cells) cause a faster production of antibodies on a second exposure/exposure to the disease;
- (memory cells) provide long term immunity;

(b)
Outline the role of membrane proteins in the movement of specific ions at specific times in the transmission of nerve impulses.
[4]
Markscheme
- (during depolarization) Na+ channels open;
- allowing Na+ to flow into the axon;
- (during repolarization) K+ channels open;
- allowing K+ to flow out of the axon;
- the Na+/K+ pump returns the (axon) membrane to the resting potential;
- by moving 3Na+ out and 2K+ in;

(c)
Describe the barriers that exist to hybridization between species.
[4]
Markscheme
- courtship behaviour is often complex and unique to a species;
- (at several stages in courtship ritual) rejection occurs if characteristic behaviour not exhibited;
- species-specific egg fertilization;
- compatibility of acrosome with vitelline layer;
- inability of successfully attached wrong species sperm to develop continuity with egg membrane;
- sterility of interspecific hybrids;
- due to differences in chromosome number;
