Question 23M.2.HL.TZ1.3
Date | May 2023 | Marks available | [Maximum mark: 6] | Reference code | 23M.2.HL.TZ1.3 |
Level | HL | Paper | 2 | Time zone | TZ1 |
Command term | Explain, Outline | Question number | 3 | Adapted from | N/A |
Antibiotics such as penicillin are secreted by fungi and other microorganisms in soil. By secreting them, a microorganism can inhibit the growth of a competitor.
In research published in 2014, nearly 3000 antibiotic resistance genes were discovered in soil microorganisms, giving resistance to 18 different antibiotics. The types of antibiotic resistance gene varied between soil types.
Explain how natural selection could increase the prevalence of an antibiotic resistance gene in a species of soil bacterium.
[3]
- if antibiotic is in the environment/soil there is selection (pressure);
- bacteria without resistance (gene) die / converse;
- bacteria with resistance (gene) reproduce
OR
bacteria exchange/obtain resistance genes using plasmids/by conjugation; - offspring inherit (the gene for) resistance/resistance passed on (to offspring);
Do not award marks for general statements about natural selection – answers must refer to antibiotic resistance.

There are viruses in soils that are pathogens of animals. Outline a reason for antibiotics in soil not eliminating these viruses.
[1]
- viruses lack metabolism/plasma membranes/cell walls / viruses are not livingorganisms;
- antibiotics kill/target bacteria/prokaryotes but not viruses;
- viral pathogens of animals use animal metabolism (which is not affected by antibiotics);

Explain the reasons for antibiotics secreted into soil not harming insects or other animals in the soil.
[2]
- antibiotics (only) affect/kill/block processes in bacteria/prokaryotes / do not affect eukaryotes;
- metabolism/protein synthesis/ribosomes/cell walls not targeted in insects/animals/eukaryotes;
- no cell walls in animals (so antibiotics cannot attack cell walls);
- antibiotics are secreted (by microbes/fungi) to prevent competition (with other microbes);
