Question SPM.1A.HL.TZ0.19
| Date | May Specimen-2023 | Marks available | [Maximum mark: 1] | Reference code | SPM.1A.HL.TZ0.19 |
| Level | HL | Paper | 1A | Time zone | TZ0 |
| Command term | Question number | 19 | Adapted from | N/A |
The graph shows the effect of methylation on the expression of MT1E, a gene involved in the control of prostate cancer development. Patients with a reduced expression of this gene are more likely to develop prostate cancer.
[Source: © 2017 Demidenko et al. 2017. Decreased expression of MT1E is a potential biomarker of
prostate cancer progression. Oncotarget, 8, pp. 61709–61718. Distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0). Image redrawn and reannotated.]
What are effects of MT1E methylation?
A. It reduces transcription of MT1E, increasing the risk of prostate cancer.
B. It increases translation of MT1E, reducing the risk of prostate cancer.
C. It reduces replication of MT1E, reducing the risk of prostate cancer.
D. It increases the chances of mutation in proto-oncogenes, increasing the risk of prostate cancer.
[1]
A
