Question 18M.3.HL.TZ2.12c
| Date | May 2018 | Marks available | [Maximum mark: 3] | Reference code | 18M.3.HL.TZ2.12c |
| Level | HL | Paper | 3 | Time zone | TZ2 |
| Command term | Outline | Question number | c | Adapted from | N/A |
A protein expressed by the gene carotene desaturase (CTP1) was introduced into Golden rice (Oryza sativa) through genetic engineering. Bioinformatics were used to determine if the protein sequence matched any allergenic proteins (proteins that trigger an allergic reaction). The table shows the results from the alignment of the CTP1 protein with proteins from moth, soybean and dust mite that are known to be allergenic.
Genes such as the one coding for CTP1 can be located by searching for open reading frames. Outline how open reading frames are identified.
[3]
a. a DNA sequence with a promoter, a start and a stop codon
b. start codon is ATG
c. stop codon is TAA/TAG/TGA
d. nucleotide sequence with a considerable length
e. named bioinformatics software
OR
ORF finder
Allow other verifiable answer.
